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p34cdc2 is thought to be activated by cyclin through dephosphorylation at tyrosine residues. Activated p34cdc2 kinase is involved in a number of mitotic events such as nuclear envelope breakdown and chromosome condensation through phosphorylation of serine/threonine residues of substrates such as nuclear lamins, histones, pp60c-src, nucleolin and RNA polymerase II. It is then inactivated by a tyrosine kinase. Anti-p34cdc2 can be used in western blotting, immunoprecipitation and immunohistochemistry. The antibody precipitates an active kinase.
- Product categories: Primary Monoclonal Antibodies>Apoptosis & Cell Biology - Pkg Size: 50 µg - Clone: 17 - Target: p34cdc2 Serine/Threonine Kinase - Research Area: Apoptosis, Cell Biology - Applications: FC - Concentration: 0.2 mg/ml - Formulation: This DyLight® 550 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. - Storage and Stability: This DyLight® 550 conjugate is stable when stored at 2-8°C. Do not freeze.
Suggested application(s)Flow cytometry
Clone17
Marker550, Dylight®
Storage temperature+4°C
Quantity50 ug
The stock indication is not contractual: this data is constantly changing and may vary depending on the quantities requested.