Single Cell Analysis

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Functional Genomics


Fluidigm - Polaris™

Fluidigm - Polaris™

Seamlessly integrate cell and molecular biology at a single-cell level

The Polaris™ lets you select single-cells from heterogeneous cell samples and hold them in separated, environmentally controlled nL reaction chambers, making it possible to measure each cell’s response. It is an integrated fluidic circuit (IFC). The Polaris™ takes functional genomics to a new level.
 

  • Select and isolate single-cells

  • Perturb with RNA, transcription factor, virus, or small molecules

  • 6 groups with individual interval and concentration dosing plans

  • Image cells to monitor viability or immunophenotype

  • Lyse, reverse-transcribe, amplify, and harvest for mRNA sequencing

Fluidigm

Imaging System


Fluidigm Hyperion Imaging System

Fluidigm - Hyperion™ Imaging System

A comprehensive system for unprecedented visualization

The Hyperion™ brings together CyTOF® technology with impressive imaging capability and gives you Imaging Mass Cytometry™ (IMC™). It is a high-parameter imaging system that enables simultaneous imaging of more than 37 protein markers at once when using Maxpar® metal-tagged antibodies. The system paves the way for understanding complex cellular phenotypes and their interrelationships. Subcellular resolution enables new pathology insights, new biomarker correlations and cell interactions.
The Hyperion™ Imaging System has been named as the top innovation of 2017 by The Analytical Scientist.
 

  • High Multiplex IHC with 135 channels without spectral overlap

  • Provides a context as the subcellular resolution (1 micron) gives tissue architecture and morphology

  • No need for serial sections, meaning that you preserve precious samples and reduce variability

Fluidigm

Automated Cell Counter


DeNovix - CellDrop™

DeNovix - CellDrop™

Cell counting without slides

With unique DirectPipette™ Technology that eliminates plastic slides and glass hemocytometers from routine cell counting for reduction in consumable costs and environmental benfits. Dual fluorescence and brightfield optics, variable height sample chamber, and powerful, easy-to-use analysis software. Stand-alone instrument with touchscreen compatible with barcode reader and label printer.
 

  • AO/PI - Fluorescence cell counting and viability
  • Determine yeast cell number and viability using FDA/PI
  • Label-free total cell counts with brightfield
  • Combined measurements of Brightfield, AO, and PI measurements
  • Green Fluorescent Protein (GFP)
  • Assess transfection efficiency via Green Fluorescence Protein

DeNovix

Real-Time Cell Analyzer


Real-Time Cell Analyzer

ACEA - xCELLigence Real Time Cell Analysis Instruments

A new paradigm for cell-based assays

The xCELLigence instruments provide a powerful yet simple solution for live cell analysis. You get non-invasive, label-free and real-time all at once with a real-time cell analyzer.
 

  • No markers or dyes required
  • Compatible with orthogonal assays
  • Real-time kinetics readout
  • Fast as it reads in seconds
  • Easy workflow
  • Broad applications
ACEA

Microdissection


Fluidigm - AccuLift Laser Capture Microdissection System

Fluidigm - AccuLift Laser Capture Microdissection System

Two Lasers in One - A Renaissance in Laser Capture Microdissection

The Fluidigm AccuLift System is an unparalleled LCM system that harnesses the power of gentle infrared (IR) laser capture and ultraviolet (UV) laser cutting in one unique platform in combination with a novel suite of cap consumables, extraction reagents and user-friendly software.
 

  • Precise - Accurate and gentle capture of samples down to a single-cell level

  • Simple - Easy, streamlined workflow

  • Efficient - Novel caps and instrument cap arm that increase lifting efficiency for improved DNA, RNA or protein extraction

  • Consistent - Cellular biomolecule integrity preserved for the most consistent downstream results

Fluidigm

Single-cell RNA- and DNA-seq


Takara Bio SMART-Seq Single Cell Kit

Takara Bio - SMART-Seq Single Cell Kit

Single-cell transcriptome analysis with ultimate sensitivity

Generate high-quality, full-length cDNA directly from single cells known to have low RNA content, e.g. peripheral blood mononuclear cells. The SMART-Seq Single Cell Kit provides exceptional sensitivity and reproducibility. 
 

  • Easy, plate-based workflow 
  • Unparalleled sensitivity and reproducibility, especially for cells with low RNA content and for nuclei 
  • Robust, full-length chemistry 
  • Easily scalable workflow as it the kit has high-throughput capabilities and is automation-friendly
Takara Bio

Single Cell Preparation


Fluidigm - C1

Fluidigm - C1

Automated solution for single-cell genomics

The C1 is the strongest platform, with the most applications, for single-cell processing. Get even more capabilities with the large number of applications available.
 

  • Isolate and process individual cells

  • Streamlined workflow and intuitive interface

  • Protocols for preparing single cells for NGS sequencing

  • Protocols for preparing single cells for real-time PCR

Fluidigm