Single Cell Analysis
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Sample preparation simplified
Applied Cells - MARS
Sample preparation simplified
Get high recovery, high purity and high throughput.
The MARS (Multiphysics Automated Reconfigurable Separation) platform is a modular cell processing system with modules that can be customized for various cell separation and purification workflows. Utilizing acoustic force, the Cell Processing Chip (CPC) separates cells based on differences in physical parameters. Specific sub-populations can be isolated in-flow using the matrix-free immuno-magnetic cell separation module. Target cell surface markers are labeled using a biotinylated antibody and isolated using streptavidin conjugated magnetic beads.
- Ease-of-use and walk-away operation
- Centrifuge-free wash with higher recovery and lower cell loss
- White blood cell separation from whole blood in 12 minutes with 98 % viability
- Negative and Positive selection can be done directly from whole blood
- Compatible with 5 mL (FACS) tubes, 15 mL tubes and 50 mL tubes
- Small footprint - dimensions: 52 cm x 40 cm x 51 cm (L x W x H)
Fluidigm - Polaris™
Seamlessly integrate cell and molecular biology at a single-cell level
The Polaris™ lets you select single-cells from heterogeneous cell samples and hold them in separated, environmentally controlled nL reaction chambers, making it possible to measure each cell’s response. It is an integrated fluidic circuit (IFC). The Polaris™ takes functional genomics to a new level.
Select and isolate single-cells
Perturb with RNA, transcription factor, virus, or small molecules
6 groups with individual interval and concentration dosing plans
Image cells to monitor viability or immunophenotype
Lyse, reverse-transcribe, amplify, and harvest for mRNA sequencing
Fluidigm - Hyperion™ Imaging System
A comprehensive system for unprecedented visualization
The Hyperion™ brings together CyTOF® technology with impressive imaging capability and gives you Imaging Mass Cytometry™ (IMC™). It is a high-parameter imaging system that enables simultaneous imaging of more than 37 protein markers at once when using Maxpar® metal-tagged antibodies. The system paves the way for understanding complex cellular phenotypes and their interrelationships. Subcellular resolution enables new pathology insights, new biomarker correlations and cell interactions.
The Hyperion™ Imaging System has been named as the top innovation of 2017 by The Analytical Scientist.
High Multiplex IHC with 135 channels without spectral overlap
Provides a context as the subcellular resolution (1 micron) gives tissue architecture and morphology
No need for serial sections, meaning that you preserve precious samples and reduce variability
Automated Cell Counter
DeNovix - CellDrop™
Cell counting without slides
With unique DirectPipette™ Technology that eliminates plastic slides and glass hemocytometers from routine cell counting for reduction in consumable costs and environmental benfits. Dual fluorescence and brightfield optics, variable height sample chamber, and powerful, easy-to-use analysis software. Stand-alone instrument with touchscreen compatible with barcode reader and label printer.
- AO/PI - Fluorescence cell counting and viability
- Determine yeast cell number and viability using FDA/PI
- Label-free total cell counts with brightfield
- Combined measurements of Brightfield, AO, and PI measurements
- Green Fluorescent Protein (GFP)
- Assess transfection efficiency via Green Fluorescence Protein
Real-Time Cell Analyzer
ACEA - xCELLigence Real Time Cell Analysis Instruments
A new paradigm for cell-based assays
The xCELLigence instruments provide a powerful yet simple solution for live cell analysis. You get non-invasive, label-free and real-time all at once with a real-time cell analyzer.
- No markers or dyes required
- Compatible with orthogonal assays
- Real-time kinetics readout
- Fast as it reads in seconds
- Easy workflow
- Broad applications
Fluidigm - AccuLift Laser Capture Microdissection System
Two Lasers in One - A Renaissance in Laser Capture Microdissection
The Fluidigm AccuLift System is an unparalleled LCM system that harnesses the power of gentle infrared (IR) laser capture and ultraviolet (UV) laser cutting in one unique platform in combination with a novel suite of cap consumables, extraction reagents and user-friendly software.
Precise - Accurate and gentle capture of samples down to a single-cell level
Simple - Easy, streamlined workflow
Efficient - Novel caps and instrument cap arm that increase lifting efficiency for improved DNA, RNA or protein extraction
Consistent - Cellular biomolecule integrity preserved for the most consistent downstream results
Single-cell RNA- and DNA-seq
Takara Bio - SMART-Seq Single Cell Kit
Single-cell transcriptome analysis with ultimate sensitivity
Generate high-quality, full-length cDNA directly from single cells known to have low RNA content, e.g. peripheral blood mononuclear cells. The SMART-Seq Single Cell Kit provides exceptional sensitivity and reproducibility.
- Easy, plate-based workflow
- Unparalleled sensitivity and reproducibility, especially for cells with low RNA content and for nuclei
- Robust, full-length chemistry
- Easily scalable workflow as it the kit has high-throughput capabilities and is automation-friendly
Single Cell Preparation
Fluidigm - C1
Automated solution for single-cell genomics
The C1 is the strongest platform, with the most applications, for single-cell processing. Get even more capabilities with the large number of applications available.
Isolate and process individual cells
Streamlined workflow and intuitive interface
Protocols for preparing single cells for NGS sequencing
Protocols for preparing single cells for real-time PCR